Protein expression is the process of synthesizing, regulating, and modifying proteins within a living organism. The global protein expression market was evaluated at USD 1,693.6 million in 2017. The protocol for expression of proteins makes use of expression vectors, competent cells, reagents, instrument, and services. The reagents are the estimated to hold the largest share due to large volume used in the bio-experiments. The significant growth in the protein expression industry is primarily due to the increasing funds from government and non-government organization for protein research, the soaring prevalence of chronic diseases, rising life science industry.
Insight by Product & Services
Different types of products and services offered by the market players are expression vectors, competent cells, reagents, instruments and services. Reagents held the largest share of 53.1% in the market in 2017, globally. The increasing number of research and development activities in lifesciences industry is the key factor leading to the growth in the protein expression reagents market during the forecast period.
Insight by Systems
Among the various systems being used in the market, the prokaryotic expression system is the largest contributor with 39.7% share in the protein expression market in 2017, globally. This category includes escherichia coli systems, and other prokaryotic expression systems. The largest share of prokaryotic expression system is due to the cost effectiveness, as it is less expensive over other available categories; and the wide usage of E.coli systems in industries. Other types of systems used in the market include yeast systems, mammalian cell, insect cell, cell-free systems, and algal-based systems.
Insight by Application
Based on application, the market is categorized into therapeutics, research, and industries. The increasing number of chronic diseases on a global level led to the application of protein expression majorly in finding therapy for chronic diseases. Also, the increasing number of lifescience and bio-pharmaceutical industries also adds to the largest contribution of therapeutics category to the protein expression market. Other key application include research purposes and commercial productions of proteins in industries.
GLOBAL PROTEIN EXPRESSION MARKET SHARE, BY APPLICATION (2017)
Insight by End User
Pharmaceutical and biotechnology companies are the largest end user in the protein expression market. The category’s largest contribution is due to the large production of recombinant proteins for therapeutics, and the growing advancement in technology with respect to protein research. Further, other end users to the protein expression market includes academic research institutes, contract research organizations (CROs), others industries such as food processing, brewery, leather, paper, chemical and cosmetic industries. The CROs are projected to witness high demand and register fastest CAGR of 13.7% during the forecast period.
The market observes major challenge in maintaining aseptic conditions required to run the experiment, and also in addressing the complexities associated to the purification of the proteins. Moreover, the products and services offered by manufacturers are costly, that will restrain the growth of the global protein expression market.
Growth Drivers and Opportunity
The increasing investment from government and non-government organization with respect to protein research and the growing life science industry are the primary factors driving the growth of the protein expression industry. The increase in prevalence of chronic diseases that requires therapeutic approach will also spur the growth of the market.
Several research conducted reports the profiling of protein expression using of microfluidic technology. For instance, a study supported by the Cancer Research UK (CRUK), on the Multiplexed single cell analysis in solid tumors using a miniaturized microfluidic assay. This growing adoption of microfluidic devices in profiling protein will provide manufacturers to advance and explore the opportunities that the technology holds.
The number of suppliers in the protein expression market is medium, since the products utilized in protein profiling and expression needs to follow stringent government regulations. Further, the threat of forward integration is low leading to a low bargaining power of suppliers in the market. Presence of large number of buyers in the market offers manufacturers revenue growth opportunities in the market.
Geographically, North America is the largest market for protein expression products and services, globally. The largest contribution of the region is due to the adaptation of technologically advanced products, and the increasing government and non government funds for protein research. The North American protein expression market is also driven by the surge in prevalence of chronic diseases, and the growing number of life science and bio-pharmaceutical industries in the region.
GLOBAL PROTEIN EXPRESSION MARKET SHARE, BY REGION (2017)
Moreover, the protein expression industry is expected to be driven by emerging economies of Asia-Pacific, such as China, and India. This leads to the fastest growth in Asia-Pacific at a CAGR of 13.9% during the forecast period. The growth in the region is also supported by supported by increasing investment in lifescience industry and the increase in prevalence of chronic diseases in the region.
The major player in the global protein expression market include New England Biolabs, Inc., Thermo Fisher Scientific Inc., QIAGEN N.V., Takara Bio Inc., Lonza Group Ltd., Merck KGaA, Promega Corporation, Genscript Biotech Corporation, Agilent Technologies Inc., and Bio-Rad Laboratories, Inc.
The market players are launching new and technologically advanced products and services to maintain their competency and market share. For instance, in March 2018, Aragen Bioscience, Inc. announced the expansion of its RapTr cell line development services to be included in CHO-GS cell lines. The addition of suite protein expression and analytical services will provide flexibility in the development of cell lines and generation of high quality proteins.