Status : Published Published On : Apr, 2019 Report Code : VRHC1198 Industry : Healthcare Available Format : Page : 117

U.S. Protein Expression Market – Analysis and Forecast (2019–2024)

Industry Insights by Product & Services (Expression Vectors, Competent Cells, Reagents, Instruments, Services), by Systems (Prokaryotic Expression Systems, Yeast Expression Systems, Mammalian Cell Expression Systems, , Algal-Based Expression Systems, Insect Cell Expression Systems, Cell-Free Expression Systems), by Application (Therapeutics, Research, Industrial), by End-User (Academic Research Institutes, Contract Research Organizations, Pharmaceutical And Biotechnology Companies, Others)

Industry Overview

The U.S. protein expression market is expected to grow at a CAGR of 11.6% during the forecast period with its market size predicted to reach USD 1.2 billion by 2024. The U.S. protein expression market is primarily driven by the factors such as the increasing prevalence of chronic diseases, increasing investment for recombinant protein expression, advancement in technology for expression systems, increasing geriatric population, and robust growth of the life sciences industry in the country. Prokaryotic expression systems and mammalian cell expression systems are the major contributors to the protein expression industry in the region.

U.S. Protein Expression Market Highlight

Market Segmentation

Insight by Product & Services

Based on product & services, protein expression market is categorized into expression vectors, competent cells, reagents, instruments, and services. Reagents hold the largest share in the U.S. market. Reagents are the key component for the successful protein expression and with the increasing number of research and development activities for protein biologics in the life sciences industry; the demand for reagents is anticipated to increase significantly.

Insight by Systems

Based on systems, the market is segmented into prokaryotic expression systems, yeast expression systems, cell-free expression systems, mammalian cell expression systems, algal-based expression systems, and insect cell expression systems. Among the various systems being used in the market, the prokaryotic expression system holds the largest share in the U.S. protein expression market. Prokaryotic expression systems are further categorized into Escherichia coli systems and other prokaryotic expression systems. The largest share of prokaryotic expression system is due to the cost-effectiveness, as it is less expensive over other available categories; and the various applications of E. coli systems in research and industrial applications.

Yeast expression system market is further categorized into saccharomyces systems, K. lactis systems, Pichia systems, and others. Among different types of mammalian cell expression systems, Chinese hamster ovary systems are the most commonly used expression system. Similarly, among insect cell expression systems, baculovirus systems witness the largest demand in the market.

Insight by Application

Based on application, the market is categorized into therapeutics, research, and industries. The increasing number of chronic diseases on a global level led to the application of protein expression majorly in finding therapy for chronic diseases. Also, the increasing number of life science and biopharmaceutical industries also adds to the largest contribution of therapeutics category to the protein expression market. Other key applications include research purposes and commercial productions of proteins in industries.

Insight by End User

Based on end users, the market is segmented into academic research institutes, contract research organizations, pharmaceutical and biotechnology companies, and others. Pharmaceutical and biotechnology companies are the largest end user in the U.S. protein expression market. This is primarily due to the large production of recombinant proteins for therapeutics, and the growing advancement in technology with respect to protein research. The highest demand for protein expression products and services is anticipated from CROs during the forecast period.

Industry Dynamics

Growth Drivers

The increasing prevalence of chronic diseases, increasing funding for recombinant protein expression from government and non-government organizations, advancement in technology for expression systems, increasing geriatric population, and robust growth of the life sciences industry in the country are the primary growth drivers for the U.S. protein expression industry. Different government and non-government organizations are funding investment for the development of protein biologics. Technological advancements such as microfluidics have advanced the approach of protein expression system such as a cell-free expression system. Cell-free expression systems provide a very high yield of proteins are being proved efficient for the development of protein biologics.

Challenges

The high cost of reagents and equipment, complexities associated with purification of proteins are the key challenges faced by the U.S. protein expression industry.

Competitive Insight

Some of the key players operating in the U.S. protein expression market are New England Biolabs, Inc., Thermo Fisher Scientific Inc., QIAGEN N.V., Takara Bio Inc., Lonza Group Ltd., Merck KGaA, Promega Corporation, Genscript Biotech Corporation, Agilent Technologies Inc., and Bio-Rad Laboratories, Inc.

PRIMARY RESEARCH INTERVIEWS - BREAKDOWN

U.S. Protein Expression Market Analysis

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Research Methodology

  •  Desk Research / Pilot Interviews
  •  Build Market Size Model
  •  Research and Analysis
  •  Final Deliverabvle