Status : Upcoming Report Code : VRHC1022 Industry : Healthcare Available Format :

Global Single-Use Bioreactor Market – Analysis and Forecast (2018-2024)

Industry Insights by Product (Single-Use Bioreactor System, Media Bags, Filtration Assemblies, and Others), by Type of Cell (Bacterial Cell, Yeast Cell, Mammalian Cell and Others), by Type of Molecule (Vaccines, Gene-Modified Cells, Monoclonal Antibodies, Stem Cell and Other Molecules), by Application (Research and Development, Bioproduction Process and Process Development), by End-User (Biopharmaceutical Manufacturer and R&D Departments)

Industry Overview

Single-use bioreactor (SUB) is used for the production of biopharmaceutical products due to its high performance and flexibility in the production of multiple drugs. It is mainly used in research and development and manufacturing of biopharmaceuticals. The global single-use bioreactor market is growing at significant rate due to growing biologic market, patent expiry of products and reduced automation complexity. The market has witnessed high demand for single-use bioreactor systems over the last few years, due to its advantages such as elimination of validation issues and shortened down time.

Single-Use Bioreactor Market Highlights

Market Segmentation

Insight by Product

The global market has been segmented by product into single-use bioreactor system, media bags, filtration assemblies, and others. SUB system account for the largest share in the market, due to increasing adoption of SUB systems by pharmaceutical companies and its advantages such as reduced down time and elimination of validation issues. Moreover, it decreased the risk of cross contamination due to use of new bags for each run.

Insight by Type of Cell

The global single-use bioreactor market has also been segmented by type of cell into bacterial cell, yeast cell, mammalian cell and others. The mammalian cell segment is estimated to account largest share and is expected to grow at fastest rate in the market due to increasing application of mammalian cell in biologics manufacturing due to its high therapeutic efficiency.

Insight by Type of Molecule

The different types of molecule single-use bioreactor market is segmented into are vaccines, gene-modified cells, monoclonal antibodies, stem cell and other molecules. The monoclonal antibodies are estimated to account the largest share in the market due to increase in demand for SUB system which provides greater productivity and flexibility, less requirement of manpower and low investment cost.

Insight by Application

The single-use bioreactor market has also been segmented by application into research and development, bioproduction process and process development. The bioproduction process segment is estimated to account largest share in the market due to increasing adoption of SUB system due to its easy implementation and low investment cost.

Insight by End-User

Different end-users in the single-use bioreactor market are biopharmaceutical manufacturer and R&D departments. Biopharmaceutical manufacturer account the larger share in the market due to increasing number of SUB products in biopharmaceutical companies.

Industry Dynamics

Growth Drivers

The increasing use of SUB among small companies, reduced environmental impact, and patent expiry of products are the primary growth drivers for single-use bioreactor market. The use of SUB provides immense flexibility to the pharmaceutical companies. It helps pharmaceutical companies in time saving, reduces the energy efficiency and complexity of automation. Moreover, single-use production plant have low contamination risk and is significantly cost saving.

Moreover, growing biologics market, reduced automation complexity, and ease in cultivation of marine organisms are also fueling the growth of the global single-use bioreactor market. Automation of stainless steel system and single-use systems differs in complexity. Stainless-steel reactors need a continuous cleaning and sterilization which results in a high consumption of chemicals and ultrapure water.

In addition, technological advancement in SUB is also boosting the growth of the single-use bioreactor industry. For instance, manufacturers are focusing on introducing high-power SUB and the control systems are also being improved to help in multiple unit operations. New systems are also being designed specifically for microbial fermentation. Moreover, improvement in the design, sensor system, and film technology of bioreactor is also increasing adoption of SUB.


The need for improved single-use sensors, regulatory concerns related to SUB, standardization of single-use designs and issues regarding leachable and extractable are the major challenges for the growth of single-use bioreactor market.

Industry Ecosystem

Manufacturers are ensuring that products bring about cost savings in biopharmaceutical companies. Manufacturers are focused on improving mixing; reduce complexity, and avoiding leakage, and other integrity issues, which help them to retain their market share.

Geographic Overview

Geographically, Europe is the largest single-use bioreactor market as the government in the region supports for new biologics. Some of the other factors leading to the growth of the European market are growing research activities, reduced environmental impact, technological advancement, patent expiry of products, and increasing adoption of SUB systems.

Asia-Pacific is observed to witness fastest growth in the market. Growing biologics market and increasing use of SUB in small and startup companies are the primary factors boosting the growth of the market. Moreover, growing research activities and reduced automation complexity are also driving the growth of the Asia-Pacific market.

Competitive Insight

Key players in the industry are investing in the development of innovative and advance products, which is strengthening their position in the market. On March 2018, WuXi Biologics announced that it has selected ABEC’s Custom Single Run disposable bioreactors for its new commercial manufacturing facility in Wuxi city, China. Sartorius Stedim Biotech, Eppendorf, Merck Millipore, Cesco Bioengineering, GE Healthcare, Applikon Biotechnology, Danaher, Thermo Fisher Scientific, Parker Hannifin, Cellexus and Celltainer Biotech are some of the key players offering single-use bioreactor.

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Research Methodology

  •  Desk Research / Pilot Interviews
  •  Build Market Size Model
  •  Research and Analysis
  •  Final Deliverabvle
Single-Use Bioreactor Market